Postdoc in Alpha Cell Biology - University of Copenhagen

We are looking for a highly motivated, dynamic and driven researcher with a PhD or equivalent to join the section for Cell Biology and Physiology (CBP), Department of Biology, University of Copenhagen to work in the Knudsen group. The candidate should have a strong background in cell biology, physiology and/or molecular biology. The starting date is 1st of January 2026 or as soon as possible thereafter. The postdoctoral researcher position is funded as part of an ERC Starting grant.

Information on the department can be found at: https://www1.bio.ku.dk/

Our research

We are interested in the fundamental mechanisms that control secretion of the hormone glucagon from pancreatic alpha cells, and how changes in alpha cell function contribute to the regulation of whole-body metabolism and physiology. We work on cell cultures, primary tissue from genetically modified mouse models and human donors. Using biochemical assays, live cell time lapse microscopy and in-situ perfusion, combined with in vivo experiments we explore how alpha cell function is regulated.

Your job

We are looking for individuals interested in exploring alpha cell biology. As a postdoctoral researcher you will participate in a project where we will investigate kinase signaling in alpha cells. The aim of the project is to integrate the mechanisms that regulate glucagon secretion. As part of the project, you will directly work with the generation of viral constructs and use live cell FRET imaging to understand paracrine signaling in alpha cells. You will also have the opportunity to participate in the maintenance of several colonies of genetically modified mice and design and perform in vivo experiments to follow up on observations made in isolated islets.

Profile
We are looking for a highly motivated and enthusiastic researcher who, in addition to the desired expertise stated above, has the following skills and qualifications:

Required qualifications:

• PhD in cell biology, physiology, metabolism or similar.
• Experience with confocal FRET microscopy
• Expertise in molecular cloning
• Expertise in cellular pH
• Experience in Islet research
• Proven track record showing scientific productivity with publications in peer-reviewed journals.
• Proficient communication skills and ability to work in multi-disciplinary teams.
• Experience in supervising other researchers at different levels.

Place of employment

The place of employment is at the Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art equipment for Islet and metabolic research.

Terms of employment
The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 2,5 years. Starting date is 1st of January, 2026, or after agreement.

The position is covered by the Memorandum on Job Structure for Academic Staff.

Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.

Questions
For further information please contact Jakob G Knudsen Jgknudsneballamberjeffrey68@bio.ku.dkchen-massey.dkbrown.dkmartinez.dk

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply for position’. Furthermore, your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).
2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
4. List of publications.

Deadline for applications: 2 October 2025, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.