Computational Biologist - Cancer Genomics at BRIC, University of Copenhagen

We are looking for an experienced and motivated computational biologist to join our team commencing October 1st, 2025 or as soon as possible hereafter.

Our group and research

The Weischenfeldt lab is working on delineating the mutational mechanisms and clonal evolution of cancer, with a particular focus on genomic structural rearrangements. We use computational and experimental approaches including WGS, single-cell, and long-read sequencing together with chromatin conformation techniques to understand how cancers mutate and evolve, which we are applying to cancer patient material in close collaboration with clinical colleagues at the hospital.

The successful candidates will be joining a larger team of cross-disciplinary cancer researchers, with the aims to identify mutational processes and clonal evolution in cancer.

Starting date: October 1st or after agreement.

Principal supervisor is group leader, Prof Joachim Weischenfeldt, BRIC and Rigshospitalet, sophia94kristydaviseric59joachim.weischenfeldt@bric.ku.dksmith-johnson.dkwilliams.dk, Phone: +453545 6040

Your job
You will be working with high-dimensional data including short- and long-read sequencing data from patient-derived tumour material in collaboration with other team members. Your job will include data science management and development of novel and executing existing computational methods including machine learning and deep learning methods to integrate genomics, transcriptomics and epigenomics data. You will take part in larger projects that aims to investigate genomic-epigenomic interactions and cancer evolution trajectories.

The tasks will include running and maintaining computational pipelines, as well as processing and analysis of different data modalities. You will have the opportunity to develop data science methodologies. The position involves interdisciplinary research through exchange of ideas and results with clinicians and researchers.

Profile
We are looking for highly motivated and enthusiastic scientists with the following competencies and experience:

Essential experience and skills:

• You have a Masters in computational biology, bioinformatics or related areas
• You are highly experienced in working with NGS and long read sequencing data
• You have an active interest in genetics and clonal evolution
• Proficient communication skills and ability to work in teams
• Excellent English skills written and spoken

Desirable experience and skills:

• You have a PhD in computational biology, bioinformatics or related areas
• Experience with machine learning and statistics
• Experience with tumour evolution reconstruction
• Knowledge on mutational mechanisms in cancer
• Publications as co-author or first author in a related area
• Fellowships, grants and prizes

Place of employment

The place of employment is at BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and access to HPC.
Please read more about our research at https://www.bric.ku.dk/Research/weischenfeldt-group/

Terms of employment

The average weekly working hours are 37 hours per week.

Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Taxation and AC (the Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 18,07 % to your pension fund.

Questions
For further information please contact Joachim Weischenfeldt, joachim.weischenfeldtbchangharmonbryce@dickerson-nelson.dkbric.ku.dkhoffman-lee.dkarnold-green.dk

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).

2. CV incl. education, work/research experience, language skills and other skills relevant for the position.

3. A certified/signed copy of Master of Science certificate, and PhD certificate, if applicable. If the PhD is not completed, a written statement from the supervisor will do.

4. List of publications – if any.

Letters of recommendation

Furthermore, the applicant should provide at least one letter of recommendation. To be taken into consideration, the letter must be signed by the supporting person with institutional letter head and in PDF-format. Please make sure that an easy match between the recommendation letter and the individual applicant is possible.

Application deadline: 20 August 2025, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.